Prairie City Vacations from $388

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Your Prairie City Vacation

Take the hassle out of planning your next great adventure with a Prairie City vacation package. Whether you've come for its history, food or something else, there's an inexhaustible array of experiences to be had. Neal Smith National Wildlife Refuge is one of the famous attractions to include on your itinerary during a trip to Prairie City. Whoever you're escaping with and whatever your bank balance, your dream Prairie City vacation is just a few clicks away with Expedia.

The Latest Prairie City vacation packages

Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Ankeny/Des Moines

AmericInn by Wyndham Ankeny/Des Moines

3 out of 5
Price was $450, price is now $388 per person
$388
per person
Jan 28 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Amarillo (AMA) to Des Moines (DSM)
8/10 Very Good! (818 reviews)
The room was nice. Staff was very pleasant.

Reviewed on Nov 23, 2025

Cobblestone Inn & Suites - Winterset, IA

Cobblestone Inn & Suites - Winterset, IA

2.5 out of 5
Price was $490, price is now $398 per person
$398
per person
Jan 28 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Amarillo (AMA) to Des Moines (DSM)
9.2/10 Wonderful! (708 reviews)
We found a bug on our bed, it bite Russ.

Reviewed on Nov 5, 2025

My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA

3 out of 5
Price was $448, price is now $394 per person
$394
per person
Jan 28 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Amarillo (AMA) to Des Moines (DSM)
9/10 Wonderful! (758 reviews)
Very clean, quiet, and great staff!

Reviewed on Dec 15, 2025

Qube Hotel

Qube Hotel

2.5 out of 5
Price was $473, price is now $422 per person
$422
per person
Jan 28 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Amarillo (AMA) to Des Moines (DSM)
8.4/10 Very Good! (726 reviews)
Great staff! Enjoyed our stay.

Reviewed on Dec 3, 2025

Comfort Inn & Suites Ankeny - Des Moines

Comfort Inn & Suites Ankeny - Des Moines

2.5 out of 5
Price was $463, price is now $416 per person
$416
per person
Jan 28 - Jan 31
found 1 day ago
Roundtrip non-stop flight included
Amarillo (AMA) to Des Moines (DSM)
8.8/10 Excellent! (708 reviews)
Slept well. Comfortable beds and great room

Reviewed on Dec 1, 2025

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Discover the most popular places to visit in Prairie City

Nice trails to walk.

Neal Smith National Wildlife Refuge

You can spend time exploring the galleries in Neal Smith National Wildlife Refuge during your trip to Prairie City. While you're in the area, wander around the natural setting.

Neal Smith National Wildlife Refuge

Prairie City Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $160 total per night from Jan 4 to Jan 5
$160 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,066 reviews)
Comfy and stylish lobby and rooms, delicious cafe

Reviewed on Dec 13, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Dec 21 to Dec 22
$100 total
Dec 21 - Dec 22
Total with taxes and fees
9.2/10 Wonderful! (1,003 reviews)
Clean room

Reviewed on Dec 14, 2025

Home2 Suites by Hilton Des Moines at Drake University
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Dec 25 to Dec 26
$71 total
Dec 25 - Dec 26
Total with taxes and fees
8.4/10 Very Good! (1,682 reviews)
Old outside appearance but when you get inside the room was like brand new. Super clean. Staff accommodated the hockey equipment of the boys. Great experience!

Reviewed on Dec 15, 2025

Days Inn & Suites by Wyndham Des Moines Airport
See all 608 properties in Prairie City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Prairie City Vacation Packages

Prairie City Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)
Population
1,700
Top Sights
Neal Smith National Wildlife Refuge, Toad Valley Golf Course and Valle Drive In

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Frequently asked questions

How much does a Prairie City vacation package cost?
You'll find cheap prices from $388 on Expedia for your Prairie City getaway. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Prairie City costs.
What are the cheapest months to go to Prairie City?
You can generally find reduced prices and better availability in November, December and January. Browse our cheap Prairie City vacation packages and you could land some great off-season deals.
How many days is enough for Prairie City?
Generally, a handful of days is enough to see the main attractions during your Prairie City vacation. But if you prefer to have time to chill out or go on day trips, think about extending your trip.
How to find the best Prairie City package deals?
Start your search for a Prairie City package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Popular locations," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the ideal Prairie City package deal straight away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Prairie City escape off to a flying start.
Is it cheaper to book a Prairie City vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your car rental, hotel and flight into one great-value price and you could save hundreds of dollars. You'll typically score a better deal than booking each component separately. And you'll still get the freedom to create a customized Prairie City vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Prairie City?
If you've got your Prairie City vacation dates confirmed, book as early as you can to snap up some outstanding deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spontaneous trips? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Prairie City vacation packages?
Jet off on your dream trip to Prairie City with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait until your next paycheck — we've joined forces with online lender Affirm to give you more flexibility and choice. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden or late payment fees, you can easily stay on budget and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.